Treatment of Megaloblastic Anaemia with Vitamin B12

Megaloblastic anaemia due to vitamin B12 malabsorption associated with long-term metformin treatment.

Changes in serum vitamin B12 levels in patients with megaloblastic anaemia treated with folic acid.

In 21 patients with megaloblastic anaemia associated with the tropical malabsorption syndrome serum vitamin B(12) levels have been measured serially before and during parenteral folic acid therapy. In 11 patients there was a significant rise in serum B(12) levels, reaching a peak three to 17 days after starting the folic acid. In three of these cases, absorption of labelled B(12) was the same b...

The absorption of vitamin B12 in megaloblastic anaemia associated with pregnancy.

The absorption of (60)CoB(12) has been studied in a group of patients suffering from megaloblastic anaemia associated with pregnancy and in a control group. The mean urinary excretion of (60)CoB(12) in the patients with megaloblastic anaemia is not significantly different from that of the control group. Five of the 30 patients showed a value towards the lower limit of normal, but the serum vita...

Immunoglobulin deficiency responding to vitamin B12 in two elderly patients with megaloblastic anaemia.

Two elderly patients with vitamin B12 deficiency were found to have low immunoglobulin levels. These returned to normal on treatment with vitamin B12.

Vitamin B12 deficiency--a major cause of megaloblastic anaemia in patients attending a tertiary care hospital.

BACKGROUND Folate and vitamin B12 deficiencies have been known to cause megaloblastic anaemia. Since the deficiencies of these two vitamins are very common in Pakistani population, it would be imperative to investigate their role in causing megaloblastic anaemia. The objective of this study was to find out the contribution of folate and vitamin B12 deficiencies in causing megaloblastic anaemia ...